Assisted fertilization in women of advanced reproductive age: Quo vadis?

Abstract

Oocyte and embryo donation has become a frequent procedure in infertile women
of advanced reproductive age, with a high pregnancy rate. In these pregnancies,
the incidence of adverse obstetric events (hypertensive disorders, gestational
diabetes, operative delivery, among others) and perinatal mortality increases.
Multiple pregnancies significantly increase the risks, so single embryo transfer is
recommended. Patients should have a previous comprehensive medical examination
including cardiovascular and psychological evaluation, avoiding treatment in women
with chronic diseases that significantly increase risks. This symposium will review
infertility management in women of advanced reproductive age with own and
donated oocytes, obstetric and perinatal complications as well as ethical aspects and
special considerations to consider in this type of treatment.