Comparación de las tasas de nacidos vivos entre la transferencia de blastocitos congelados y frescos para la infertilidad masculina

Nesrin  Polat; Hale  Bayram; Yaprak  Donmez Cakil; Belgin  Selam; Mehmet  Cincik

doi:10.31403/rpgo.v70i2686

Authors

Nesrin Polat Instituto de Estudios de Posgrado Programa de Máster en Embriología Clínica, Maltepe University
Hale Bayram Departamento de Histología y Embriología, Facultad de Medicina, Universidad de Maltepe
Yaprak Donmez Cakil Departamento de Histología y Embriología, Facultad de Medicina, Universidad de Maltepe
Belgin Selam Departamento de Obstetricia y Ginecología, Centro de FIV, Facultad de Medicina, Universidad Acıbadem
Mehmet Cincik Departamento de Histología y Embriología, Facultad de Medicina, Universidad de Maltepe

DOI:

https://doi.org/10.31403/rpgo.v70i2686

Keywords:

Fertilization in vitro, Vitrification, Embryo Transfer, Pregnancy rate, Live birth

Abstract

Background: In recent years, with the development of assisted reproductive
techniques, different in vitro fertilization-embryo transfer protocols have been
developed. Embryo cryopreservation has emerged as an alternative to fresh embryo
transfer. The superiority of fresh versus frozen-thawed embryo transfer in terms of
pregnancy outcome varies among studies. Objective: To compare pregnancy and
live birth rates resulting from fresh and frozen-thawed blastocyst transfers in male
infertile couples. Methods: In this retrospective study, 803 intracytoplasmic sperm
injection-embryo transfer cycles (304 fresh and 499 frozen-thawed) from 2019 to
2022 were reviewed. The results of pregnancy rates were compared as a function of
embryo transfer method. In addition, pregnancy rates were evaluated as a function
of embryo transfer method and maternal age. Results: The mean age of women
in the fresh and frozen-thawed blastocyst transfer groups and the proportion
of fresh and frozen-thawed transfers in the age groups were similar. Pregnancy
rates of all cases differed between the two groups, with higher rates observed in
the group that underwent fresh blastocyst transfer. However, live birth rates were
similar. In addition, when pregnancy rates were compared according to maternal
age, no significant differences were found. In all cases and fresh blastocyst transfer,
pregnancy rates decreased with increasing age. Conclusion: Our results indicate
comparable live birth rates with fresh embryo transfer compared to frozen-thawed
transfers in male factor infertility.