Endometrial premalignant lesions.

Abstract

Genuine hyperplasia, macroscopically be confused with cancer; but it is distinguished because the latter presents necrosis and friability. Adenomatous hyperplasia can be mistaken for cancer; in the opinion of several authors (Gundberg, Kaplan), atypical changes are related to prolonged estrogen stimulation. Novack acknowledge the existence of some correlation between post-menopausal hyperplasia and adenocarcinoma. Wilson and Beecham and Carrington expressed the adenomatous hyperplasia exhibits sufficient evidence to be considered as precancerous lesions or carcinoma in-situ. Prolonged estrogen stimulation in women genetically predisposed to cancer, can initiate carcinogenesis. You may metaplasia and endometrial polyps can be considered as pre-malignant lesions in the elderly woman.