Clinical evaluation of two two-phase and three-phase preparations based norgestrel /

Abstract

458 women were evaluated during 3585 cycles in a randomized, open controlled study designed to compare two two-phase and three-phase preparations based Norgestrel / Etilnilestradiol. The three preparations are not effective contraceptives and pregnancies were recorded. Cycle control was good with all three, but the incidence of bleeding was ost mom with three phase. With this preparation full hormonal intake is well below the lower fixed doses of Norgestrel / Ethinyl as a combined preparation (more Norgestrel 300 mcg 30 mcg EE..) In the original aspect ratio 10: 1. It is concluded that the hormone dose wobble opens the possibility of hormonal contraception with lower intake of what is possible when a fixed dose regimen is used.