horionic gonadotropin, a serum marker of preeclampsia?

Abstract

To determine the correlation between beta chorionic gonadotropin levels measured in the second trimester of pregnancy and the risk of presenting preeclampsia. DESIGN: Prospective, descriptive study. MATERIAL: A 85 pregnant women in the second quarter was determined the beta subunit of human chorionic gonadotropin serum being followed until the end. RESULTS: Maternal age 29.4 añoss average, prepregnancy weight average 55.7 kilos. Mean gestational age at sampling 20.6 weeks, 38 nulliparous and 47 multiparous. The plasma concentration of chorionic gonadotropin beta had an average of 32.988 mIU / ml and a range of 5000 to 140,000 mIU / mL. Average gestational age at birth 38 weeks, 53 vaginal deliveries and 32 cesarean deliveries. Preeclampsia occurred in 14 of 85 pregnant women (16%), 10 with mild preeclampsia and 4 with severe preeclampsia. Chorionic gonadotropin beta in severe preeclampsia ranged from 60000-140000 mIU / mL and the slightest of 53000-71000 mIU / mL, highly significant difference. CONCLUSION: The value of the chorionic gonadotropin beta in the second trimester, could be considered a risk factor for predicting the possible occurrence of preeclampsia. We should make wider to deny or confirm this hypothesis studies.