Carcinoma primario de células de Merkel vulvar

Duly Torres-Cepeda; Martha Rondon-Tapia; Eduardo Reyna-Villasmil

doi:10.31403/rpgo.v68i2442

Authors

Duly Torres-Cepeda Especialista en Ginecología y Obstetricia. Servicio de Obstetricia y Ginecología, Hospital Central “Dr. Urquinaona”, Maracaibo
Martha Rondon-Tapia Especialista en Ginecología y Obstetricia. Servicio de Obstetricia y Ginecología, Hospital Central “Dr. Urquinaona”
Eduardo Reyna-Villasmil Especialista en Ginecología y Obstetricia. Servicio de Obstetricia y Ginecología, Hospital Central “Dr. Urquinaona"

DOI:

https://doi.org/10.31403/rpgo.v68i2442

Keywords:

Vulva, Carcinoma, Merkel cell, Vulvar neoplasms

Abstract

Merkel cells were originally described in the stratum basale of the epidermis with
neuroendocrine properties. Merkel cell carcinoma of the vulva is an extremely
rare and highly aggressive neoplasm. There are few cases of these tumors, most
of which have been considered neuroendocrine tumors. The histologic origin and
etiology of this disease are controversial. It is known for his aggressive behavior
and propensity for early diffusion. Because of its rarity in this location, it is unclear
whether it behaves differently from similar skin carcinomas in other locations. A case
of primary vulvar Merkel cell carcinoma is presented. Excisional biopsy examination
revealed a 4 x 3-centimeter tumor in the posterior third of the left labium majus of the
vulva without lymph node involvement. The patient underwent radical vulvectomy
and bilateral inguinal lymph node dissection. Postoperative histological evaluation
showed no regional or distant metastases.