Colestasis del embarazo

Pedro A. Poma

doi:10.31403/rpgo.v59i38

Autores/as

Pedro A. Poma Profesor, Departamento de Obstetricia y Ginecología, Universidad de Illinois en Chicago, EE UU.

DOI:

https://doi.org/10.31403/rpgo.v59i38

Resumen

La colestasis intrahepática del embarazo (CIDE) se caracteriza por prurito en la segunda mitad del embarazo, prurito que no se asocia con otros problemas dermatológicos o sistémicos. El diagnóstico se confirma con la elevación de los niveles maternos de bilirrubina, enzimas hepáticas y ácidos biliares en ayunas. El pronóstico para el feto es serio, pues la CIDE está asociada con pasaje de meconio, partos prematuros y muerte fetal. El tratamiento con tabletas de ácido ursodeoxicólico (UDCA) mejora el prurito, las pruebas de laboratorio y disminuye los resultados fetales adversos. Para la embarazada, la CIDE es relativamente benigna; pero, se ha observado que en el futuro estas mujeres tienen un riesgo mayor de presentar problemas hepatobiliares, cáncer de la mama e hipotiroidismo que las mujeres que no tuvieron esta complicación. Se recomienda un seguimiento prolongado. Palabras clave: Ultrasonido, HDLive US, Obstetricia, Ginecología.

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